Regenerative influence of nanostructured bredigite (Ca7MgSi4O16)/anodic spark coating on biodegradable AZ91 magnesium alloy implants for bone healing

作者: Mehdi Razavi , Mohammadhossein Fathi , Omid Savabi , Daryoosh Vashaee , Lobat Tayebi

DOI: 10.1016/J.MATLET.2015.04.129

关键词:

摘要: Abstract Magnesium has been recently introduced as a novel biodegradable material for bone healing. However, the fast degradation of this results in release hydrogen which limits its clinical applications. In view that, present study, we attempt to overcome drawback using bredigite (Ca7MgSi4O16) coating. our previous work, have coated AZ91 magnesium implants with through combination anodic spark deposition (ASD) and electrophoretic (EPD) techniques. As continuation that paper, focused on vivo examination bredigite/ASD compared plain ASD uncoated substrates. The animal test greater trochanter rabbits indicated improved regeneration less inflammation upon employing implants. addition, an enhancement biodegradation was observed by reduction ion released blood plasma. summary, surface treatment promotes their healing capabilities future

参考文章(19)
Jiang Chang, Yin Xiao, Chengtie Wu, Silicate-Based Bioactive Ceramics for Bone Regeneration Application Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery. ,(2013)
Masoud Mozafari, Mehrnoush Mehraien, Daryoosh Vashaee, Lobat Tayebi, Electroconductive Nanocomposite Scaffolds: A New Strategy Into Tissue Engineering and Regenerative Medicine InTech. ,(2012) , 10.5772/51058
Kathryn F. Farraro, Kwang E. Kim, Savio L-Y. Woo, Jonquil R. Flowers, Matthew B. McCullough, Revolutionizing orthopaedic biomaterials: The potential of biodegradable and bioresorbable magnesium-based materials for functional tissue engineering Journal of Biomechanics. ,vol. 47, pp. 1979- 1986 ,(2014) , 10.1016/J.JBIOMECH.2013.12.003
M. Yazdimamaghani, M. Razavi, D. Vashaee, L. Tayebi, Microstructural and mechanical study of PCL coated Mg scaffolds Surface Engineering. ,vol. 30, pp. 920- 926 ,(2014) , 10.1179/1743294414Y.0000000307
Mehdi Razavi, Mohammadhossein Fathi, Omid Savabi, Daryoosh Vashaee, Lobat Tayebi, In vitro study of nanostructured diopside coating on Mg alloy orthopedic implants. Materials Science and Engineering: C. ,vol. 41, pp. 168- 177 ,(2014) , 10.1016/J.MSEC.2014.04.039
H. Hornberger, S. Virtanen, A.R. Boccaccini, Biomedical coatings on magnesium alloys - a review. Acta Biomaterialia. ,vol. 8, pp. 2442- 2455 ,(2012) , 10.1016/J.ACTBIO.2012.04.012
Sannakaisa Virtanen, Biodegradable Mg and Mg alloys: Corrosion and biocompatibility Materials Science and Engineering B-advanced Functional Solid-state Materials. ,vol. 176, pp. 1600- 1608 ,(2011) , 10.1016/J.MSEB.2011.05.028
Chengtie Wu, Jiang Chang, Junying Wang, Siyu Ni, Wanyin Zhai, Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic Biomaterials. ,vol. 26, pp. 2925- 2931 ,(2005) , 10.1016/J.BIOMATERIALS.2004.09.019
G. Song, S. Song, A possible biodegradable magnesium implant material Advanced Engineering Materials. ,vol. 9, pp. 298- 302 ,(2007) , 10.1002/ADEM.200600252