作者: Anton Karabinos
DOI: 10.1016/J.EJCB.2013.10.004
关键词:
摘要: We analyzed the draft genome of cephalochordate Branchiostoma floridae (B. floridae) for genes encoding intermediate filament (IF) proteins. From 26 identified IF 13 were not reported before. Four new belong to previously established group A, four B, one is homologous type II keratin E2 while remaining sequences N1 N4 could be readily classified in any groups. All eleven A and B2-type are located on same genomic scaffold arose due multiple cephalochordate-specific duplications. Another gene cluster, B. genome, contains three keratins (E1, Y1, D1), two keratin-like (C2, X1), (N1) unrelated gene, but does show similarities well defined vertebrate I or clusters. In addition, some III sequence features documented protein N2, which, however, seems share a common ancestry with D1 keratin-related C. Thus, few existed ancestor cephalochordates vertebrates, which after separation these lineages gave rise known complexities cytoplasmic I-IV proteins, as related cephalochordates, duplications, deletions divergences.