The cephalochordate Branchiostoma genome contains 26 intermediate filament (IF) genes: Implications for evolution of chordate IF proteins

作者: Anton Karabinos

DOI: 10.1016/J.EJCB.2013.10.004

关键词:

摘要: We analyzed the draft genome of cephalochordate Branchiostoma floridae (B. floridae) for genes encoding intermediate filament (IF) proteins. From 26 identified IF 13 were not reported before. Four new belong to previously established group A, four B, one is homologous type II keratin E2 while remaining sequences N1 N4 could be readily classified in any groups. All eleven A and B2-type are located on same genomic scaffold arose due multiple cephalochordate-specific duplications. Another gene cluster, B. genome, contains three keratins (E1, Y1, D1), two keratin-like (C2, X1), (N1) unrelated gene, but does show similarities well defined vertebrate I or clusters. In addition, some III sequence features documented protein N2, which, however, seems share a common ancestry with D1 keratin-related C. Thus, few existed ancestor cephalochordates vertebrates, which after separation these lineages gave rise known complexities cytoplasmic I-IV proteins, as related cephalochordates, duplications, deletions divergences.

参考文章(29)
Harald Herrmann, Michael Hesse, Michaela Reichenzeller, Ueli Aebi, Thomas M. Magin, Functional complexity of intermediate filament cytoskeletons: From structure to assembly to gene ablation International Review of Cytology-a Survey of Cell Biology. ,vol. 223, pp. 83- 175 ,(2002) , 10.1016/S0074-7696(05)23003-6
Andreas Erber, Dieter Riemer, Helmut Hofemeister, Marc Bovenschulte, Reimer Stick, Georgia Panopoulou, Hans Lehrach, Klaus Weber, Characterization of the Hydra lamin and its gene: A molecular phylogeny of metazoan lamins. Journal of Molecular Evolution. ,vol. 49, pp. 260- 271 ,(1999) , 10.1007/PL00006548
Anton Karabinos, Dieter Riemer, Georgia Panopoulou, Hans Lehrach, Klaus Weber, Characterisation and tissue-specific expression of the two keratin subfamilies of intermediate filament proteins in the cephalochordate Branchiostoma. European Journal of Cell Biology. ,vol. 79, pp. 17- 26 ,(2000) , 10.1078/S0171-9335(04)70003-5
Jian Wang, Anton Karabinos, Alexander Zimek, Michael Meyer, Dieter Riemer, Clare Hudson, Patrick Lemaire, Klaus Weber, Cytoplasmic intermediate filament protein expression in tunicate development: a specific marker for the test cells. European Journal of Cell Biology. ,vol. 81, pp. 302- 311 ,(2002) , 10.1078/0171-9335-00246
Alba Galán, Laura Garcia-Bermejo, Nuria E. Vilaboa, Elena de Blas, Patricio Aller, Uncoupling of apoptosis and Jun/AP-1 activity in human promonocytic cells treated with DNA-damaging and stress-inducing agents. European Journal of Cell Biology. ,vol. 79, pp. 1- 9 ,(2000) , 10.1078/S0171-9335(04)70001-1
Jian Wang, Anton Karabinos, Jürgen Schünemann, Dieter Riemer, Klaus Weber, The epidermal intermediate filament proteins of tunicates are distant keratins; a polymerisation-competent hetero coiled coil of the Styela D protein and Xenopus keratin 8. European Journal of Cell Biology. ,vol. 79, pp. 478- 487 ,(2000) , 10.1078/0171-9335-00069
Michael Hesse, Alexander Zimek, Klaus Weber, Thomas M. Magin, Comprehensive analysis of keratin gene clusters in humans and rodents European Journal of Cell Biology. ,vol. 83, pp. 19- 26 ,(2004) , 10.1078/0171-9335-00354
Anton Karabinos, Jürgen Schünemann, David A.D Parry, Klaus Weber, Tissue-specific co-expression and in vitro heteropolymer formation of the two small Branchiostoma intermediate filament proteins A3 and B2 Journal of Molecular Biology. ,vol. 316, pp. 127- 137 ,(2002) , 10.1006/JMBI.2001.5298