Contrast agent stability: a continuous B-mode imaging approach.

摘要: The stability of contrast agents in suspensions with various dissolved gas levels has not been reported the literature. An vitro investigation carried out that studied combined effect varying acoustic pressure along degassing suspension environment. In this study, were introduced into different oxygen concentration levels, and their relative performance was assessed terms decay rate backscatter echoes. partial pressures those solutions ranged between 1.5 26 kPa. Two IV one arterial used: Definity, Quantison, Myomap. It found Quantison Myomap released free bubbles at high also faster degassed suspensions. for Definity did depend on air content destruction dependent pressure. Different observed by populations last two agents. physical quantity "overall backscatter" (OB) defined as integral over time suspensions, improved significantly understanding behaviour A quantitative analysis properties using a continuous imaging approach difficult to achieve. This is due fact field view representative bubble population affected ultrasound (US) field, but whole tank. Single frame insonation suggested avoid effects ultrasonic measure tank-representative backscatter. definition OB useful, however,