Serum phenytoin levels with different brands.

作者: Kishore K , Jailakhani Bl , Sharma Jn , Ahuja Gk

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摘要: Four brands of phenytoin were studied in 60 newly diagnosed epileptic patients randomly and equally placed 4 groups. Serum levels estimated by EMIT spectrophotometric methods both which gave close values with good correlation (r = 0.985). Average serum the incidence remission achieved varied within statistical scatter; thus these manifested equivalent therapeutic efficacy. In 22 level was less than 5 micrograms/ml, 9 whom attacks remained uncontrolled. 38 exceeded micrograms/ml 2 44 out weeks significantly higher (P 0.001 paired t-test) those after 3 months. remaining 16 at months 0.01).

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