Membrane Transport of Amphiphilic Compounds by Hepatocytes

摘要: Liver, being the central organ for degradation of compounds differing greatly in chemical and physical properties, must have appropriate transport systems vectorial membrane transport. Of outstanding interest are great many amphiphilic compounds, metabolites xenobiotics, which excreted hepatobiliarily, either unmetabolized or metabolized. In order to evaluate number, specificity, function hepatic substances representative characteristic substance classes their photolabile derivatives were used for: 1. Kinetic studies (K) 2. Photoaffinity labelling (P) 3. Differential photoaffinity (D)