Magnetic resonance imaging of the liver: New imaging strategies for evaluating focal liver lesions

摘要: The early detection of focal liver lesions, particularly those which are malignant, is utmost importance. resection metastases some malignancies (including colorectal cancer) has been shown to improve the survival patients. Exact knowledge number, size, and regional distribution essential determine their resectability. Almost all lesions larger than 10 mm demonstrated with current imaging techniques but smaller still relatively poor. One advantages magnetic resonance (MRI) better soft tissue contrast (compared other radiologic modalities), allows characterization in question. Developments MRI hardware software availability novel agents have further improved diagnostic yield lesion characterization. Although primary modalities for ultrasound computed tomography, recent studies suggested that most sensitive method detecting small metastatic now considered pre-operative standard diagnosis. Two developments sequences upper abdomen comprise unenhanced diffusion-weighted (DWI), keyhole-based dynamic contrast-enhanced (DCE) (4D THRIVE). DWI (b = s/mm2) (< mm) particular, useful as a road map sequence. Also, using higher b-values, calculation apparent diffusion coefficient value, true coefficient, D, perfusion fraction, f, used lesions. DCE 4D THRIVE enables high temporal spatial resolution full coverage. improves evaluation providing multiple arterial venous phases, parameters pharmacokinetic models. potential benefits terms detection, staging monitoring therapy.