Effects of naloxone on dental pain threshold following muscle exercise and low frequency transcutaneous nerve stimulation: a comparative study in man.
作者： B. OLAUSSON , E. ERIKSSON , L. ELLMARKER , B. RYDENHAG , B.-C. SHYU
DOI: 10.1111/J.1748-1716.1986.TB07818.X
关键词:
摘要: Previous studies have shown that muscle exercise and low frequency transcutaneous nerve stimulation (TNS) give rise to an analgesic effect in humans animals. Endorphin has been proposed mediate this analgesia. In investigation, the of TNS, on dental pain thresholds was studied possible involvement endorphinergic mechanisms investigated using naloxone as antagonist. Dental were measured 11 volunteers following leg or arm after TNS hands face. After (20 min) (30 either 0.8 mg (2 ml) saline injected i.v. a double-blind fashion. Pain repetitively before stimulation. Both increased threshold. Stimulation also threshold, but less than exercise. A marked increase threshold seen face These changes unaffected injections saline, except for early short-lasting reduction when The increases showed similarities suggesting common mechanism might be involved. could only partially mediated by mechanisms.
sci-hub.se 参考文章(24)
Antti Pertovaara, Pentti Kemppainen, Gunnar Johansson, Sirkka-Liisa Karonen, Dental analgesia produced by non-painful low-frequency stimulation is not influenced by stress or reversed by naloxone Pain. ,vol. 13, pp. 379- 384 ,(1982) , 10.1016/0304-3959(82)90006-9
J. Lewis, J. Cannon, J. Liebeskind, Opioid and nonopioid mechanisms of stress analgesia Science. ,vol. 208, pp. 623- 625 ,(1980) , 10.1126/SCIENCE.7367889
Ashley Grossman, Vicky Clement-Jones, 3 Opiate receptors: Enkephalins and endorphins Clinics in Endocrinology and Metabolism. ,vol. 12, pp. 31- 56 ,(1983) , 10.1016/S0300-595X(83)80028-0
Malvin N. Janal, Edward W.D. Colt, Crawford W. Clark, Murray Glusman, Pain sensitivity, mood and plasma endocrine levels in man following long-distance running: effects of naloxone. Pain. ,vol. 19, pp. 13- 25 ,(1984) , 10.1016/0304-3959(84)90061-7
Thomas B. Freeman, James N. Campbell, Donlin M. Long, Naloxone does not affect pain relief induced by electrical stimulation in man Pain. ,vol. 17, pp. 189- 195 ,(1983) , 10.1016/0304-3959(83)90142-2
Richard C. Chapman, Yoko M. Colpitts, Costantino Benedetti, Richard Kitaeff, John D. Gehrig, Evoked potential assessment of acupunctural analgesia: attempted reversal with naloxone Pain. ,vol. 9, pp. 183- 197 ,(1980) , 10.1016/0304-3959(80)90006-8
Richard J. Haier, Kimberly Quaid, J.Scott C. Mills, Naloxone alters pain perception after jogging. Psychiatry Research-neuroimaging. ,vol. 5, pp. 231- 232 ,(1981) , 10.1016/0165-1781(81)90052-4
David J. Mayer, Donald D. Price, Amir Rafii, Antagonism of acupuncture analgesia in man by the narcotic antagonist naloxone. Brain Research. ,vol. 121, pp. 368- 372 ,(1977) , 10.1016/0006-8993(77)90161-5
D.H. Zilm, Naloxone response in non-dependent man: effect on six physiological variables. Neuropharmacology. ,vol. 19, pp. 591- 595 ,(1980) , 10.1016/0028-3908(80)90031-3
Michael L. Ahlquist, Lennart G.A. Edwall, Ove G. Franzén, Glenn A.T. Haegerstam, Perception of pulpal pain as a function of intradental nerve activity. Pain. ,vol. 19, pp. 353- 366 ,(1984) , 10.1016/0304-3959(84)90081-2