作者: R. E. Hubbard , I. A. Lang , D. J. Llewellyn , K. Rockwood
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摘要: Background. Frailty has been conceptualized as a wasting disorder with weight loss key component. However, obesity is associated disability and physiological markers also recently linked frailty, for example, increased inflammation low antioxidant capacity. We aimed to explore the relationship between frailty body mass index (BMI) in older people.Methods. Data were from 3,055 community-dwelling adults aged 65 years who participated English Longitudinal Study of Ageing. was defined both by an accumulated deficits Fried phenotype. BMI divided into five categories, waist circumference 88 cm or more (for women) 102 men) high. Analyses adjusted sex, age, wealth, level education, smoking status.Results. The association showed U-shaped curve. This consistent across different measures. lowest (FI) scores prevalence those 25-29.9. At each category, using either measure high significantly frail.Conclusions. Both phenotypic definition FI show levels among very BM Is. In view rise populations, benefits feasibility diet exercise obese should be focus urgent inquiries. circumference, even underweight people, suggests that truncal may additional target intervention.