On modulating the Physarum polycephalum plasmodium's electrical resistance, resting membrane potential and capacitance by application of nanoparticles and nanostructures

摘要: Abstract Physarum polycephalum is a model organism used in the creation of hybrid artificial-biological devices. Among its demonstrated uses biocomputing it able to grow self healing ‘wires’ which can be generate circuitry, especially following hybridisation with nano- and micro-scale circuit components. In this study P. polycephalum plasmodia were hybridised nanomaterials; graphene oxide, carbon nanotubes, calcium phosphate aluminium oxide. Observations made on toxicological effects alterations electrical properties; mean potential, period, frequency, resistance capacitance. Macroscopically, there was little evidence toxic using any these nanomaterials. Capacitance increased substantially decreased nanotube-treated plasmodia, all results for other nanomaterials being lesser magnitude. Our demonstrate that nanotubes are suitable material biohybridisation conductive cellular pathways, whilst influencing their