Compositions and methods for inducing satiety and treating non-insulin dependent diabetes emillitus, pre-diabetic symptoms, insulin resistance and related disease states and conditions

作者: Joseph M. Fayad

DOI:

关键词:

摘要: The invention provides methods of treatment that induce satiety in a subject for period at least around twenty- four hours by once-daily administration to the controlled release dosage form, wherein form is administered while fasted state and time six nine prior subject's next intended meal, comprises composition, which an enterically-coated, ileum hormone-stimulating amount nutritional substance releases majority vivo upon reaching ileum. also diagnostic tool probing health disease ileal hormones, excess or deficiencies. safe vehicle targeted deliveries chemical, pharmaceuticals, natural substances nutrition present method treating noninsulin dependent diabetes mellitus, pre-diabetic symptoms, insulin resistance, as well number states conditions including gastrointestinal disorders otherwise described herein.

参考文章(17)
Kim Krumhar, Michael Yatcilla, Janice Thompson, Herbal supplement to support weight loss ,(2005)
Kevin D. Niswender, Diana L. Williams, Denis G. Baskin, Richard W. Gelling, Gregory J. Morton, Michael W. Schwartz, James E. Blevins, Christopher J. Rhodes, Leptin action in the forebrain regulates the hindbrain response to satiety signals Journal of Clinical Investigation. ,vol. 115, pp. 703- 710 ,(2005) , 10.1172/JCI22081
Josephine M. Egan, Angela Bulotta, Hongxiang Hui, Riccardo Perfetti, GLP-1 receptor agonists are growth and differentiation factors for pancreatic islet beta cells. Diabetes-metabolism Research and Reviews. ,vol. 19, pp. 115- 123 ,(2003) , 10.1002/DMRR.357
Toshio Kashihara, Shin-Ichiro Hirai, Shunichi Itoh, Hiroyoshi Koyama, Enteric film and preparation thereof ,(1989)
Houn Simon Hsia, David Fan, Nutritional supplement composition and use ,(1997)
Donald D. Hensrud, Dietary Treatment and Long-Term Weight Loss and Maintenance in Type 2 Diabetes Obesity Research. ,vol. 9, pp. 348S- 353S ,(2001) , 10.1038/OBY.2001.141