Novel Molecular and Genetic Prognostic Biomarkers in Prostate Cancer

摘要: Prostate cancer is responsible for 3% of all deaths in the Western world men over 55 yr age. An urgent yet challenging priority biology to detect or identify sequential genetic and epigenetic events early enough through characterizing cancer-associated genes their protein products. At a specific stage, biomarkers reflect physiologic state cell might be vital identification subjects at risk developing cancer. Biomarkers have become an important diagnostic tool prostate With advent recent successes functional genomics proteomics, we are experiencing growing interest discovering more molecular-based prognostic factors that could utilized assay original needle biopsy specimen tailor primary treatment individual patients. As targeted therapy oncology becomes increasingly powerful, there significant finding markers used as targets novel biotherapies. This chapter discusses series existing emerging generated from ongoing research genomic, genetic, proteomic approaches molecular signatures such gene expression profiles.