Impact of aerobic training on fitness and quality of life in multiple sclerosis.

摘要: Fifty-four multiple sclerosis (MS) patients were randomly assigned to exercise (EX) or nonexercise (NEX) groups. Before and after 15 weeks of aerobic training, aspects fitness including maximal capacity (VO2max), isometric strength, body composition, blood lipids measured. Daily activities, mood, fatigue, disease status measured by the Profile Mood States (POMS), Sickness Impact (SIP), Fatigue Severity Scale (FSS), neurological examination. Training consisted 3 x 40-minute sessions per week combined arm leg ergometry. Expanded Disability Status (EDSS) scores unchanged, except for improved bowel bladder function in EX group. Compared with baseline, group demonstrated significant increases VO2max, upper lower extremity decreases skinfolds, triglyceride, very-low-density lipoprotein (VLDL). For group, POMS depression anger significantly reduced at 5 10, fatigue was 10. The on all components physical dimension SIP showed improvements social interaction, emotional behavior, home management, total score, recreation past times. No changes observed NEX groups FSS. Exercise training resulted had a positive impact factors related quality life.