A new type of Brazilian propolis: Prenylated benzophenones in propolis from Amazon and effects against cariogenic bacteria
作者： Vanna Francine de Castro Ishida , Giuseppina Negri , Antonio Salatino , Maria Fulgência C.L. Bandeira
DOI: 10.1016/J.FOODCHEM.2010.09.089
关键词:
摘要: Abstract Ethanol extracts of four propolis samples (E1–E4) from Manaus (Brazilian Amazon) were analysed by HPLC/DAD/ESI–MS/MS and GC/EIMS. The major constituents E2 E4 NMR (1H 13C) ESI/MS/MS. main are polyprenylated benzophenones: 7-epi-nemorosone, 7-epi-clusianone (major constituents), xanthochymol gambogenone making up a chemical profile so far unreported for Brazilian propolis. Aristhophenone, methyl insigninone, 18-ethyloxy-17-hydroxy-17,18-dihydroscrobiculatone B, derivatives dimethyl weddellianone A propolones, scrobiculatone derivative, detected as minor constituents. Triterpenoids (β-amyrins, β-amyrenone, lupeol lupenone) ubiquitous predominant in E1 E3. highly active against the cariogenic bacteria Streptococcus mitis, mutans salivarius. was more than E4, probably due to higher content 2-epi-nemorosone, while latter richer di-hydroxylated compounds.
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