Serological evidence of single and mixed infections of Rift Valley fever virus, Brucella spp. and Coxiella burnetii in dromedary camels in Kenya

作者: James Akoko , S M Thumbi , Bernard Bett , Samuel Kahariri , Mathew Muturi

DOI: 10.1371/JOURNAL.PNTD.0009275

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摘要: Camels are increasingly becoming the livestock of choice for pastoralists reeling from effects climate change in semi-arid and arid parts Kenya. As population camels rises, better understanding their role epidemiology zoonotic diseases Kenya is a public health priority. Rift Valley fever (RVF), brucellosis Q three top priority country but involvement transmission dynamics these poorly understood. We analyzed 120 camel serum samples northern to establish seropositivity rates pathogens characterize infecting Brucella species using molecular assays. found 24.2% (95% confidence interval [CI]: 16.5-31.8%) Brucella, 20.8% CI: 13.6-28.1%) 14.2% 7.9-20.4%) Coxiella burnetii valley virus respectively. 27.5% 19.5-35.5%) animals were seropositive at least one pathogen 13.3% 7.2-19.4%) two pathogens. B. melitensis was only spp. detected. The high sero-positivity indicative endemicity among populations possible has diseases. Considering strong association between human infection contact with most infections Kenya, there immediate need conduct further research determine zoonoses other humans. This information will be useful designing more effective surveillance systems intervention measures.

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