Chapter 1 Inflammation, Angiogenesis, and Lymphangiogenesis

作者: Cornelia Halin , Michael Detmar

DOI: 10.1016/S0076-6879(08)03001-2

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摘要: Abstract The growth of blood and lymphatic vessels, namely angiogenesis lymphangiogenesis, is well known to be importance for tumor metastatic spread. In fact, several therapeutic strategies are currently being pursued in the clinic interfere with these processes. By contrast, vascular remodeling associated chronic inflammatory disorders, such as psoriasis, rheumatoid arthritis or bowel disease, only now emerging a potential new target treat conditions. Animal models inflammation, which mimic phenotype important tools studying inflammation accompanying (lymph)angiogenic response vivo . This review provides brief summary our current knowledge inflammation‐induced lymphangiogenesis selected mouse that can used analyze processes It also detailed description methods, immunofluorescence fluorescence‐activated cell sorting (FACS) visualize quantitate inflamed tissues.

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