作者: Jean-Francois Masson , Yoon-Chang Kim , Louis A. Obando , Wei Peng , Arl S. Booksh
DOI: 10.1366/000370206778999139
关键词:
摘要: The sensitivity of fiber-optic surface plasmon resonance (SPR) sensors was improved by a factor at least thirteen for aqueous solutions modifying the tip geometry to allow interrogation (SP) band in near-infrared (NIR) region. This achieved tuning angle distal end SPR sensor dual taper 71° and 19°. Using low numerical aperture (NA) sensor, NA = 0.12, is necessary obtain functional working NIR Theoretical simulations using Maxwell equations demonstrated that even higher enhancement theoretically possible while maintaining narrow spectral feature upon excitation SP bands on gold surfaces. manufacture yields good agreement between theoretical experimental observations. To investigate properties these SPR-NIR sensors, sucrose ranging from 0 15 × 10−3 mole fraction were utilized. increased when used monitor biomarkers, would yield lower detection limits. smaller sensing area, compared planar or other combined with an improvement sensitivity, dramatic reduction absolute amount detected biosensors.