The role of parasite-driven selection in shaping landscape genomic structure in red grouse (Lagopus lagopus scotica).

摘要: Landscape genomics promises to provide novel insights into how neutral and adaptive processes shape genome-wide variation within among populations. However, there has been little emphasis on examining whether individual-based phenotype-genotype relationships derived from approaches such as association (GWAS) manifest themselves a population-level signature of selection in landscape context. The two may prove irreconcilable individual-level patterns become diluted by high levels gene flow complex phenotypic or environmental heterogeneity. We illustrate this issue with case study that examines the role highly prevalent gastrointestinal nematode Trichostrongylus tenuis shaping genomic signatures red grouse (Lagopus lagopus scotica). Individual-level GWAS involving 384 SNPs previously identified five explain T. burden. Here, we examine these same display between burden genetic structure across small-scale 21 sites heterogeneous parasite pressure. Moreover, identify showing directional using F(ST) outlier analysis relate population- multilocus candidate for parasite-driven were neither associated population level, nor under selection. Similarly, was no evidence candidates discuss results context ecology highlight broader consequences utility identifying