Stabilized pharmaceutical peptide compositions

作者: Birgitta Tennhammar-Ekman , Alan Harris

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摘要: Disclosed is a stabilized aqueous composition for administration to patient comprising biologically active peptide, buffer, quaternary amine-type preservative or disinfectant, and an osmotic pressure-controlling agent, which can be stored used at room temperature. The buffer stabilizes the pH of between about 4 6. preferred contains citrate and/or phosphate, disinfectant benzalkonium chloride. protects peptide contained therein from adhering container surfaces, particularly in containers made polymeric materials.

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