PREDICTORS OF SELENIUM CONCENTRATION IN HUMAN TOENAILS

摘要: To assess the validity of selenium concentration in human toenails as a measure intake and to determine other correlates toenail level, authors examined predictors within two subgroups large cohort study US women. Mean was higher among 38 consumers supplements (0.904 micrograms/g, standard deviation (SD) 0.217) than 96 nonusers (0.748 SD 0.149; p less 0.001), dose-response relation observed supplement users (Spearman's r = 0.32; 0.05). In second subgroup 677 women, use also associated with mean (0.906 0.214, 18 0.801 0.148, 659 nonusers; 0.02), significant 0.50; 0.03). The geographic variation levels consistent distribution forage crops. Toenail declined age significantly reduced cigarette smokers (mean 0.746, 0.124, 146 current 0.817, 0.159, 311 never smokers; 0.001) but not materially affected by alcohol consumption. A dietary score calculated from food frequency questionnaire failed predict demonstrating suspected inability diet questionnaires individual because highly variable composition different samples same food.(ABSTRACT TRUNCATED AT 250 WORDS)