Induction of alloxan/streptozotocin diabetes in dogs: A revised experimental technique
作者： H. R. Anderson , A. W. Stitt , T. A. Gardiner , S. J. Lloyd , D. B. Archer
DOI: 10.1258/002367793780745426
关键词:
摘要: The diabetic dog represents an excellent model for use in many aspects of diabetic research. The present paper describes, in detail, a reproducible experimental protocol for the successful induction of chemical diabetes in beagles using a combination of the 2 pancreatic beta-cell cytoxic agents alloxan and streptozotocin.
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