Characterization of the plasmidic beta-lactamase CMY-2, which is responsible for cephamycin resistance.

作者: A Bauernfeind , I Stemplinger , R Jungwirth , H Giamarellou

DOI: 10.1128/AAC.40.1.221

关键词:

摘要: The phenotype of Klebsiella pneumoniae HEL-1 indicates a plasmidic cephamycinase gene (blaCMY-2). Its sequence shows one open reading frame coding for protein 381 amino acids. CMY-2 is classified as class C beta-lactamase that closely related to the enzymes BIL-1 and LAT-1 chromosomal AmpC Citrobacter freundii. blaCMY-2 possibly was translocated onto plasmid C. freundii which spread K. pneumoniae.

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