Chiral polymeric microspheres grafted with optically active helical polymer chains: a new class of materials for chiral recognition and chirally controlled release
作者： Ci Song , Chaohong Zhang , Fangjie Wang , Wantai Yang , Jianping Deng
DOI: 10.1039/C2PY20546G
关键词:
摘要: A new class of chiral microspheres (μm in size) was prepared via suspension polymerization. The were constituted by optically active helical substituted polyacetylenes, which render the with considerable optical activity according to CD and UV-vis spectroscopy measurements. exhibited large oil-absorbency (ca. 70 g g−1 toward CHCl3). presence polymer chains enabled show remarkable recognition adsorption ability: maximum D- L-menthol 90 25 wt%, respectively. More interestingly, also demonstrated chirally controlled release under similar conditions, L- D-menthol 95 65 present open possibilities for developing materials used enantiomeric drug release.
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