Function and spatial distribution of ion channels and transporters in cell migration

摘要: Cell migration plays a central role in many physiological and pathophysiological processes, such as embryogenesis, immune defense, wound healing, or the formation of tumor metastases. Detailed models have been developed that describe cytoskeletal mechanisms cell migration. However, evidence is emerging ion channels transporters also play an important The purpose this review to examine function subcellular distribution Topics covered will be brief overview migration, involved ways by which polarized can achieved migrating cells. Moreover, model proposed combines transport with