Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes.

作者： J. M. Kim , K. W. Moore , Nancy A. Jenkins , Neal G. Copeland , T. A. Khan

DOI:

关键词:

摘要: The nucleotide sequence of a 7.2-kb segment containing the mouse IL-10 (mIL-10) gene was determined. Comparison to mIL-10 cDNA (Moore, K. W., et al. 1990. Science 248:1230; 250:494) revealed presence five exons that span approximately 5.1 kb genomic DNA. noncoding regions contain sequences have been associated with transcriptional regulation several cytokine genes. mapped chromosome 1 and human also 1.