Enhancing anti-tumor efficiency in hepatocellular carcinoma through the autophagy inhibition by miR-375/sorafenib in lipid-coated calcium carbonate nanoparticles.
作者： Pengxuan Zhao , Minsi Li , Yao Wang , Yan Chen , Chuanchuan He
DOI: 10.1016/J.ACTBIO.2018.03.022
关键词:
摘要: Sorafenib is a first-line drug for hepatocellular carcinoma (HCC). Autophagy has been shown to facilitate sorafenib resistance. miR-375 has been shown to be an inhibitor of autophagy. …
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researchgate.net 参考文章(41)
Jun-Wei Yan, Ju-Sheng Lin, Xing-Xing He, The emerging role of miR-375 in cancer. International Journal of Cancer. ,vol. 135, pp. 1011- 1018 ,(2014) , 10.1002/IJC.28563
Tian-Meng Sun, Jin-Zhi Du, Yan-Dan Yao, Cheng-Qiong Mao, Shuang Dou, Song-Yin Huang, Pei-Zhuo Zhang, Kam W Leong, Er-Wei Song, Jun Wang, None, Simultaneous Delivery of siRNA and Paclitaxel via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression ACS Nano. ,vol. 5, pp. 1483- 1494 ,(2011) , 10.1021/NN103349H
Josep M Llovet, Sergio Ricci, Vincenzo Mazzaferro, Philip Hilgard, Edward Gane, Jean-Frédéric Blanc, Andre Cosme De Oliveira, Armando Santoro, Jean-Luc Raoul, Alejandro Forner, Myron Schwartz, Camillo Porta, Stefan Zeuzem, Luigi Bolondi, Tim F Greten, Peter R Galle, Jean-François Seitz, Ivan Borbath, Dieter Häussinger, Tom Giannaris, Minghua Shan, Marius Moscovici, Dimitris Voliotis, Jordi Bruix, None, Sorafenib in Advanced Hepatocellular Carcinoma The New England Journal of Medicine. ,vol. 359, pp. 378- 390 ,(2008) , 10.1056/NEJMOA0708857
Boris K. Pliyev, Mikhail Menshikov, Differential effects of the autophagy inhibitors 3-methyladenine and chloroquine on spontaneous and TNF-α-induced neutrophil apoptosis. Apoptosis. ,vol. 17, pp. 1050- 1065 ,(2012) , 10.1007/S10495-012-0738-X
Xudong Zhang, Xiaowei Zeng, Xin Liang, Ying Yang, Xiaoming Li, Hongbo Chen, Laiqiang Huang, Lin Mei, Si-Shen Feng, The chemotherapeutic potential of PEG-b-PLGA copolymer micelles that combine chloroquine as autophagy inhibitor and docetaxel as an anti-cancer drug Biomaterials. ,vol. 35, pp. 9144- 9154 ,(2014) , 10.1016/J.BIOMATERIALS.2014.07.028
Ying-Hong Shi, Zhen-Bin Ding, Jian Zhou, Bo Hui, Guo-Ming Shi, Ai-Wu Ke, Xiao-Ying Wang, Zhi Dai, Yuan-Fei Peng, Cheng-Yu Gu, Shuang-Jian Qiu, Jia Fan, Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis. Autophagy. ,vol. 7, pp. 1159- 1172 ,(2011) , 10.4161/AUTO.7.10.16818
Scott M. Wilhelm, Lila Adnane, Philippa Newell, Augusto Villanueva, Josep M. Llovet, Mark Lynch, Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling Molecular Cancer Therapeutics. ,vol. 7, pp. 3129- 3140 ,(2008) , 10.1158/1535-7163.MCT-08-0013
Vassiliki Karantza, Eileen White, Role of autophagy in breast cancer. Autophagy. ,vol. 3, pp. 610- 613 ,(2007) , 10.4161/AUTO.4867
Ying Chang, Wei Yan, Xingxing He, Lemeng Zhang, Chuanjiang Li, Hai Huang, Gary Nace, David A. Geller, Jusheng Lin, Allan Tsung, miR-375 inhibits autophagy and reduces viability of hepatocellular carcinoma cells under hypoxic conditions. Gastroenterology. ,vol. 143, pp. 177- 187 ,(2012) , 10.1053/J.GASTRO.2012.04.009
Yogesh B. Patil, Suresh K. Swaminathan, Tanmoy Sadhukha, Linan Ma, Jayanth Panyam, The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials. ,vol. 31, pp. 358- 365 ,(2010) , 10.1016/J.BIOMATERIALS.2009.09.048