Antibacterial activities of the methanol extracts of Albizia adianthifolia , Alchornea laxiflora , Laportea ovalifolia and three other Cameroonian plants against multi-drug resistant Gram-negative bacteria

摘要: Abstract In the last 10 years, resistance in Gram-negative bacteria has been increasing. The present study was designed to evaluate vitro antibacterial activities of methanol extracts six Cameroonian medicinal plants Albizia adianthifolia , Alchornea laxiflora Boerhavia diffusa Combretum hispidum Laportea ovalifolia and Scoparia dulcis against a panel 15 multidrug resistant bacterial strains. broth microdilution used determine minimal inhibitory concentration (MIC) bactericidal (MBC) extracts. preliminary phytochemical screening conducted according reference qualitative methods. Results showed that all contained compounds belonging classes polyphenols triterpenes, other chemicals being selectively distributed. best were recorded with bark root A. as well L. extract, MIC values ranging from 64 1024 μg/mL on 93.3% fifteen tested bacteria. lowest value 64 μg/mL extract Enterobacter aerogenes EA289. Finally, results this provide evidence activity suggest their possible use control phenotypes.