Chemoenzymatic synthesis of (S)-duloxetine using carbonyl reductase from Rhodosporidium toruloides.

作者: Xiang Chen , Zhi-Qiang Liu , Chao-Ping Lin , Yu-Guo Zheng

DOI: 10.1016/J.BIOORG.2016.02.002

关键词:

摘要: … Although RtSCR9 displayed a remarkably higher activity in the presence of Fe 2+ and Mn 2+ , the metal chelator EDTA slightly reduced the activity, indicative of the non-metal …

参考文章(56)
Ya-Jun Wang, Xiao-Qing Liu, Xi Luo, Zhi-Qiang Liu, Yu-Guo Zheng, Cloning, expression and enzymatic characterization of an aldo-keto reductase from Candida albicans XP1463 Journal of Molecular Catalysis B-enzymatic. ,vol. 122, pp. 44- 50 ,(2015) , 10.1016/J.MOLCATB.2015.08.018
Erna Xun, Zhi Wang, Jimin Zhao, Jixun Guo, Kinetic resolution of (R, S)-2-(2-chloro-1-hydroxyethyl) thiophene via immobilizing lipase from Alcaligenes sp. onto magnetic nanoparticles Journal of Chemical Technology & Biotechnology. ,vol. 90, pp. 492- 499 ,(2015) , 10.1002/JCTB.4336
Zhi-Qiang Liu, Peter James Baker, Feng Cheng, Ya-Ping Xue, Yu-Guo Zheng, Yin-Chu Shen, Screening and Improving the Recombinant Nitrilases and Application in Biotransformation of Iminodiacetonitrile to Iminodiacetic Acid PLoS ONE. ,vol. 8, pp. e67197- ,(2013) , 10.1371/JOURNAL.PONE.0067197
Ahmed Kamal, M. Shaheer Malik, Ahmad Ali Shaik, Shaik Azeeza, Synthesis of enantiomerically pure γ-azidoalcohols by lipase-catalyzed transesterification Tetrahedron-asymmetry. ,vol. 19, pp. 1078- 1083 ,(2008) , 10.1016/J.TETASY.2008.03.028
Yoshito Fujima, Masaya Ikunaka, Toru Inoue, Jun Matsumoto, Synthesis of (S)-3-(N-Methylamino)-1-(2-thienyl)propan-1-ol: Revisiting Eli Lilly's Resolution−Racemization−Recycle Synthesis of Duloxetine for Its Robust Processes Organic Process Research & Development. ,vol. 10, pp. 905- 913 ,(2006) , 10.1021/OP060118L
Adam D. J. Calow, Elena Fernández, Andrew Whiting, Total synthesis of fluoxetine and duloxetine through an in situ imine formation/borylation/transimination and reduction approach Organic and Biomolecular Chemistry. ,vol. 12, pp. 6121- 6127 ,(2014) , 10.1039/C4OB01142B
Karsten Niefind, Jörg Müller, Bettina Riebel, Werner Hummel, Dietmar Schomburg, The Crystal Structure of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Suggests the Structural Basis of its Metal Dependency Journal of Molecular Biology. ,vol. 327, pp. 317- 328 ,(2003) , 10.1016/S0022-2836(03)00081-0
Jacob A. Friest, Yukari Maezato, Sylvain Broussy, Paul Blum, David B. Berkowitz, Use of a robust dehydrogenase from an archael hyperthermophile in asymmetric catalysis-dynamic reductive kinetic resolution entry into (S)-profens. Journal of the American Chemical Society. ,vol. 132, pp. 5930- 5931 ,(2010) , 10.1021/JA910778P
Masaru WADA, Ayumi YOSHIZUMI, Yuki FURUKAWA, Hiroshi KAWABATA, Makoto UEDA, Hiroshi TAKAGI, Shigeru NAKAMORI, Cloning and overexpression of the Exiguobacterium sp. F42 gene encoding a new short chain dehydrogenase, which catalyzes the stereoselective reduction of ethyl 3-oxo-3-(2-thienyl)propanoate to ethyl (S)-3-hydroxy-3-(2-thienyl)propanoate. Bioscience, Biotechnology, and Biochemistry. ,vol. 68, pp. 1481- 1488 ,(2004) , 10.1271/BBB.68.1481