Treatment of Advanced Non Small Cell Lung Cancer in Routine Care: A Retrospective Analysis of 212 Consecutive Patients Treated in a Community Based Oncology Group Practice

摘要: Treatment outcome data generated in prospective trials are intrinsically biased due to necessary selection criteria. Therefore the results obtained may not reflect actual impact of current treatment options for an unselected general population. We analysed modalities and 212 consecutive patients with non small cell lung cancer stages IIIB IV who were seen a community based oncology group practice between 6/1995 6/2006. 93 presented stage 119 IV. Chemotherapy was given 194/212 (92%), 114 (54%) received palliative radiation at one point during treatment. consisted chemotherapy only 86 (40%) 6 patients. 12 best supportive care only. Patients have survival rates 12, 24 36 months 64%, 27% 21% respectively 40%, 19% 11% respectively. The median is 16 11 In multivariate analysis incorporating factors (IIIB vs. IV), age (70 70 years) performance status (WHO 0/1 2/3) independent survival. These retrospective concerning , response toxicity setting confirm published phase II-III studies indicate that can be transferred into routine care.