Thyroid Hormone and Myocardial Mitochondria
作者： José Marín-García
DOI: 10.1007/978-1-4614-4599-9_22
关键词:
摘要: The ability of thyroid hormone to regulate energy utilization was first recognized more than 100 years ago and is still a contemporary topic in research. To date, we do not understand the molecular events by which controls this essential function. Energy, form ATP, currency required for life, mitochondrion its principal source. This fact has made organelle an obvious target action. In addition providing about 90 % cell, these acquired organelles also play roles cell signaling survival, two other regulatory cascades that are possible targets
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Michael K Hansen, Thomas M Connolly, Nuclear receptors as drug targets in obesity, dyslipidemia and atherosclerosis. Current opinion in investigational drugs. ,vol. 9, pp. 247- 255 ,(2008)
Douglas C. Wallace, Animal models for mitochondrial disease. Methods of Molecular Biology. ,vol. 197, pp. 3- 54 ,(2002) , 10.1385/1-59259-284-8:003
Kevin R. Short, Jonas Nygren, Rocco Barazzoni, James Levine, K. Sreekumaran Nair, T3 increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3 American Journal of Physiology-endocrinology and Metabolism. ,vol. 280, ,(2001) , 10.1152/AJPENDO.2001.280.5.E761
T. Komiya, M. Sakaguchi, K. Mihara, Cytoplasmic chaperones determine the targeting pathway of precursor proteins to mitochondria. The EMBO Journal. ,vol. 15, pp. 399- 407 ,(1996) , 10.1002/J.1460-2075.1996.TB00370.X
Jose Marin-Garcia, Radha Ananthakrishnan, Michael J. Goldenthal, Heart mitochondrial DNA and enzyme changes during early human development Molecular and Cellular Biochemistry. ,vol. 210, pp. 47- 52 ,(2000) , 10.1023/A:1007031919298
M J Evans, R C Scarpulla, Interaction of nuclear factors with multiple sites in the somatic cytochrome c promoter. Characterization of upstream NRF-1, ATF, and intron Sp1 recognition sequences. Journal of Biological Chemistry. ,vol. 264, pp. 14361- 14368 ,(1989) , 10.1016/S0021-9258(18)71686-4
D Katz, M.A. Lazar, Dominant negative activity of an endogenous thyroid hormone receptor variant (alpha 2) is due to competition for binding sites on target genes. Journal of Biological Chemistry. ,vol. 268, pp. 20904- 20910 ,(1993) , 10.1016/S0021-9258(19)36872-3
A.B. Chung, G Stepien, Y Haraguchi, K Li, D.C. Wallace, Transcriptional control of nuclear genes for the mitochondrial muscle ADP/ATP translocator and the ATP synthase beta subunit. Multiple factors interact with the OXBOX/REBOX promoter sequences. Journal of Biological Chemistry. ,vol. 267, pp. 21154- 21161 ,(1992) , 10.1016/S0021-9258(19)36810-3
R C Scarpulla, M C Kilar, K M Scarpulla, Coordinate induction of multiple cytochrome c mRNAs in response to thyroid hormone. Journal of Biological Chemistry. ,vol. 261, pp. 4660- 4662 ,(1986) , 10.1016/S0021-9258(17)38552-6
Jianming Wang, Hans Wilhelmsson, Caroline Graff, Hong Li, Anders Oldfors, Pierre Rustin, Jens C. Brüning, C. Ronald Kahn, David A. Clayton, Gregory S. Barsh, Peter Thorén, Nils-Göran Larsson, Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression Nature Genetics. ,vol. 21, pp. 133- 137 ,(1999) , 10.1038/5089