Metabolism of the Fusarium Mycotoxins T-2 Toxin and HT-2 Toxin in Wheat.
作者： Alexis V. Nathanail , Elisabeth Varga , Jacqueline Meng-Reiterer , Christoph Bueschl , Herbert Michlmayr
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摘要: To investigate the metabolic fate of HT-2 toxin (HT2) and T-2 (T2) in wheat (Triticum aestivum L.), an untargeted metabolomics study utilizing stable isotopic labeling liquid chromatography–high resolution mass spectrometry was performed. In total, 11 HT2 12 T2 derived planta biotransformation products were annotated putatively. addition to previously reported mono- diglucosylated forms HT2, evidence for formation HT2-malonyl-glucoside feruloyl-T2, as well acetylation deacetylation obtained first time. monitor kinetics metabolite formation, a time course experiment conducted involving Fusarium head blight susceptible variety Remus resistant cultivar CM-82036. Biotransformation reactions observed already at earliest tested point (6 h after treatment), formed metabolites showed different kinetic profiles. After ripening, less than 15% toxins added plants determined be ...
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