作者: A. Murat Eren , Özcan C. Esen , Christopher Quince , Joseph H. Vineis , Hilary G. Morrison
DOI: 10.7717/PEERJ.1319
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摘要: Advances in high-throughput sequencing and ‘omics technologies are revolutionizing studies of naturally occurring microbial communities. Comprehensive investigations lifestyles require the ability to interactively organize visualize genetic information incorporate subtle differences that enable greater resolution complex data. Here we introduce anvi’o, an advanced analysis visualization platform offers automated human-guided characterization genomes metagenomic assemblies, with interactive interfaces can link data from multiple sources into a single, intuitive display. Its extensible approach distills dimensions about each contig, offering dynamic unified work environment for exploration, manipulation, reporting. Using re-analyzed publicly available datasets explored temporal genomic changes within populations through de novo single nucleotide variations, linked cultivar single-cell metatranscriptomic Anvi’o is open-source empowers researchers without extensive bioinformatics skills perform communicate in-depth analyses on large datasets.