CO2 STIMULATION OF THE CORNEA : A COMPARISON BETWEEN HUMAN SENSATION AND NERVE ACTIVITY IN POLYMODAL NOCICEPTIVE AFFERENTS OF THE CAT
作者： Xiaojie Chen , Juana Gallar , Miguel A. Pozo , Manuel Baeza , Carlos Belmonte
DOI: 10.1111/J.1460-9568.1995.TB01105.X
关键词:
摘要: Excitation of nociceptors by low pH has been proposed as a cause of pain following tissue injury. Here we have studied the effect of pH reductions caused by application of CO2 pulses to the cornea on the activity of corneal afferent nerves of the cat and on the magnitude of pain sensations in humans. Single‐unit activity was recorded from corneal afferent fibres in anaesthetized cats. The corneal receptive field of A‐delta or C polymodal nociceptive units was exposed for 30 s to a gas mixture with different concentrations of CO2 …
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