Cognitive deficits and its relation with psychopathology and global functioning in first episode schizophrenia.

摘要: Abstract Aim The aim was to examine the cognitive deficits profile in first episode schizophrenia patients as well correlation between deficits, psychopathology and global functioning. Better understanding of these various facets this debilitating illness is imperative planning treatment, thereby limiting decline Methods Forty-nine with duration less than two years comprised sample. A comprehensive battery neuropsychological tests, Positive Negative Syndrome Scale WHO Disability Assessment schedule were administered assess functions, functioning respectively. Results Cognitive deficit quotient for each patient calculated. In cohort 16.3% had 25% 38.8% 25–50% 36.7% 50–75% 8.2% more 75% deficits. More 50% present showed domains attention, executive functions learning memory. Psychopathology significantly correlated symptoms motor speed, attention functions. Step wise linear regression analysis that illness, (sustained attention), function (response inhibition), negative positive predicted level at varied levels. Conclusions multiple observed cohort. Attention There a need longitudinal studies larger sample course progress illness.