Fetal and neonatal bone health: update on bone growth and manifestations in health and disease.

摘要: The neonatal period is classically described as the first 28 days of life, but owing to fact that changes in skeletal tissue occur at a somewhat slower pace than those other organ systems, events few months are considered herein. Neonatal bone health problem growing interest and concern because increasing recognition its impact upon childhood, adolescent even adult health. Osteoporosis adulthood often has roots childhood some forms may be prevented by proper attention premature infant likely suffers lifelong decreased mineral density result early birth lack adequate stores typically present full-term infants. Adequate embryogenesis, growth development system multifactorial under influence host genes, factors enzymes. evaluation dysplasias their beyond scope this paper will not discussion. Here focus on adequacy mineralization metabolic aspects fetal skeleton, effect birth, both preterm term, maternal illness well diseases.