Reduced protein adsorption on plastics via direct plasma deposition of triethylene glycol monoallyl ether

作者: Dierk Beyer , Wolfgang Knoll , Helmut Ringsdorf , Jenn-Hann Wang , Richard B. Timmons

DOI: 10.1002/(SICI)1097-4636(199708)36:2<181::AID-JBM6>3.0.CO;2-G

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摘要: The direct plasma-induced deposition of tri(ethylene glycol) monoallyl ether is reported. RF plasma polymerization this monomer was carried out under both continuous wave (CW) and pulsed operation. major focus work optimization the degree retention C-O-C bonds starting during process. This successfully accomplished using low power CW runs duty cycles experiments. Spectroscopic analysis films revealed a strong dependence film composition on employed. In particular, an unusually high level chemistry compositional control demonstrated for studies, with varying in steady, progressive fashion sequential changes ratios to off times. controllability despite relatively volatility monomer. utility approach introducing polyethylene oxide (PEO) structures solid substrates evaluated via protein adsorption studies. Radiolabeled bovine albumin studied plasma-modified poly(ethylene teraphthalate) (PET) substrates. Dramatic reductions initial were observed PET samples having maximal PEO content relative its untreated surfaces. Good stability adhesion underlying observed, as evidenced from prolonged immersion plasma-treated surfaces aqueous solution. Overall, results obtained present provide additional support one-step process reduce biological fouling surface units.

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