A quantitative post-mortem study of schistosomiasis mansoni in man.

摘要: Summary A technique for the quantitative recovery of S. mansoni from human cadavers was presented. Analysis data 197 autopsies indicated that nearly all worm pairs were recovered. The procedure is moderately time-consuming but not difficult, and can be performed with simple equipment little interference in autopsy routine. Evidence heavy infection most common cases Symmers' clay-pipestem fibrosis liver. In over half untreated there more than 160 pairs, whereas only those without 10 pairs. It postulated a prerequisite development fibrosis. Schistosomal pulmonary arteritis cor pulmonale, when present, associated fibrosis. other gross evidence disease attributable to single case ulcerative colitis massively infected child (1,608 pairs). Cadavers portal or postnecrotic cirrhosis had light infections. When liver spleen weights increased, nor they related intensity infection. The number eggs feces reflected burden absence fibrosis, although great individual variation. apparently cirrhosis, fewer per pair found cases. This, together mixture lightly heavily instances would make difficult ante-mortem estimation gram did change significantly age infection. Routine fecal examinations been frequently positive harboring pairs. The tissues infection, showed changes burden. tissue increased older persons, decreased increasing infection; latter rapid destruction distribution worms vary greatly an proportion small intestine, striking decrease rectosigmoid colon, frequent site oviposition subjects cirrhosis. The ratio male female recovered slightly greater one no infection. In rare instances, recovered; these, few found, dead generally tissues, indicating previous bisexual post-mortem suggest infections, including many years' duration, are consequence, obviously do exclude possibility produce significant evident at autopsy.