Use of previous screening mammograms to identify features indicating cases that would have a possible gain in prognosis following earlier detection.

摘要: False-negative screening mammograms generally refer to breast cancers that were overlooked or misinterpreted at screening. An important question is whether earlier detection could have made a difference in the prognosis of women concerned. We reviewed and diagnostic 234 screen-detected interval cancer cases (aged 44-84 years) diagnosed between 1991 1996 Nijmegen programme. A lesion was visible on 117 (50%) prior diagnosis cancer. Fifty-one out had poor prognostic characteristics (i.e. N+ and/or T2+) potentially benefited from an ('possible gain'). The 'possible gain' more often characterised by architectural distortion (29 vs. 10%; P=0.01) high-density mass (25 13%; P=0.06) mammogram than 58 'no cases. Our study shows non-spiculated masses are associated with possible gain prognosis. Earlier carcinomas preceded these signs may well impact mortality thus warrant extra attention radiological practice.