The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt's disease (ABCR).

摘要: Rim protein (RmP) is a high-Mr membrane glycoprotein that has been localized to the rims of photoreceptor outer segment discs, but its molecular identity unknown. Here, we describe purification RmP and present sequence mRNA. new member ATP-binding cassette (ABC) transporter superfamily. We show expressed specifically in photoreceptors predominantly segments. Further, identical recently shown be affected recessive Stargardt's disease. first ABC observed may play role photoresponse.