No Effects of Bilateral tDCS over Inferior Frontal Gyrus on Response Inhibition and Aggression

摘要: Response inhibition is defined as the capacity to adequately withdraw pre-planned responses. It has been shown that individuals with deficits in inhibiting responses tend display more aggressive behaviour. The prefrontal cortex involved both, response and aggression. While mostly associated predominantly right activity, neural components underlying aggression seem be left-lateralized. These differences hemispheric dominance are conceptualized cortical asymmetry theories on motivational direction, which assign avoidance motivation (relevant inhibit responses) approach for actions) left cortex. current study aimed directly address inverse relationship between by assessing them within one experiment. Sixty-nine healthy participants underwent bilateral transcranial Direct Current Stimulation (tDCS) inferior frontal In group we induced right-hemispheric fronto-cortical means of a combined anodal cathodal tDCS montage. second left-hemispheric A control received sham stimulation. was assessed go/no-go task (GNGT) Taylor Aggression Paradigm (TAP). We revealed poorer performance GNGT displayed during TAP. No effects either or were observed. This at odds previous brain stimulation studies applying unilateral protocols. Our results failed provide evidence support model domain absence might also indicate methodological shifting protocols failed.