Colonic fermentation to short-chain fatty acids is decreased in antibiotic-associated diarrhea

作者: Mette Rye Clausen , Helen Bonnén , Michael Tvede , Per Brøbech Mortensen

DOI: 10.1016/0016-5085(91)90384-W

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摘要: Abstract To elucidate the pathogenesis of antibiotic-associated diarrhea, colonic carbohydrate fermentation was investigated in three groups subjects—a group controls, a patients with and receiving antibiotic therapy without diarrhea. Compared markedly impaired diarrhea reflected by both very low concentrations (22.1 vs. 59.5 mmol/L; P

参考文章(41)
S.S.C. Rao, C.A. Edwards, C.J. Austen, C. Bruce, N.W. Read, Impaired colonic fermentation of carbohydrate after ampicillin Gastroenterology. ,vol. 94, pp. 928- 932 ,(1988) , 10.1016/0016-5085(88)90549-5
Hans Ruppin, Simon Bar-Meir, Konrad H. Soergel, Carol M. Wood, Milton G. Schmitt, Absorption of short-chain fatty acids by the colon. Gastroenterology. ,vol. 78, pp. 1500- 1507 ,(1980) , 10.1016/S0016-5085(19)30508-6
J H Cummings, Colonic absorption: the importance of short chain fatty acids in man. Scandinavian Journal of Gastroenterology. ,vol. 93, pp. 89- 99 ,(1984)
A.M. Stephen, A.C. Haddad, S.F. Phillips, Passage of carbohydrate into the colon Gastroenterology. ,vol. 85, pp. 589- 595 ,(1983) , 10.1016/0016-5085(83)90012-4
Hans Ulrich Bergmeyer, Methods of Enzymatic Analysis ,(1963)
J G Bartlett, N S Taylor, T Chang, J Dzink, Clinical and laboratory observations in Clostridium difficile colitis. The American Journal of Clinical Nutrition. ,vol. 33, pp. 2521- 2526 ,(1980) , 10.1093/AJCN/33.11.2521
RA Argenzio, N Miller, W von Engelhardt, Effect of volatile fatty acids on water and ion absorption from the goat colon. American Journal of Physiology. ,vol. 229, pp. 997- 1002 ,(1975) , 10.1152/AJPLEGACY.1975.229.4.997
D. R. Saunders, H. S. Wiggins, Conservation of mannitol, lactulose, and raffinose by the human colon American Journal of Physiology-gastrointestinal and Liver Physiology. ,vol. 241, ,(1981) , 10.1152/AJPGI.1981.241.5.G397
Raphael Viscidi, Sandra Willey, John G. Bartlett, Isolation rates and toxigenic potential of Clostridium difficile isolates from various patient populations Gastroenterology. ,vol. 81, pp. 5- 9 ,(1981) , 10.1016/0016-5085(81)90644-2