A new set of criteria for the diagnosis of familial Mediterranean fever in childhood

摘要: Objectives. Several sets of criteria mainly for adults have been proposed the diagnosis FMF. The aim present study is to validate most widely used diagnostic ‘Tel Hashomer’ in children and establish a new set use childhood. Methods. group consisted 170 recently diagnosed FMF patients who had mutations at both alleles. They were interviewed about presence 35 features manifestations time diagnosis. Controls consecutive without (n ¼ 141) episodes fever clinical mimicking that performance candidate was assessed by multiple logistic regression analysis. Results. sensitivity specificity Tel Hashomer our 98.8 54.6%, respectively. analysis showed 5 (fever, abdominal pain, chest arthritis family history FMF) discriminate from controls with 88.8 92.2%, two or more these five 86.5% 93.6%. Conclusion. It demonstrated although successful diagnosing childhood, its definitely low children. has high practical on an everyday basis.