Pressure Lowering Medications

作者: Liza-Sharmini Ahmad Tajudin , Yaakub Azhany

DOI: 10.5772/22575

关键词:

摘要: Glaucoma is an irreversible chronic disease; thus, management a great challenge. The main goal of treatment to prevent further nerve fibre damage. present modes include pressure-lowering medications, laser treatment, and surgical interventions, all which aim reduce IOP. Diversion aqueous humour outflow through iatrogenic fistula the sub-conjunctival space principle underlying glaucoma surgery. Surgical intervention provides sustainable constant IOP reduction but not without intraand postoperative complications (Migdal et al, 1994; Musch 2009). In fact, surgery hastens cataract formation, may necessitate (Musch 2009; AGIS group, 2000). equipment, proper operating theatre, experienced surgeon increase cost filtration invasiveness procedure interrupts natural defence mechanism eye, increasing risk infection. Laser less invasive associated with lower Similar surgery, it permanent does require high technology environment requires expensive highmaintenance machine. However, effect insufficient temporary (Glaucoma Trial Research Group, 1995). Manipulation production mainstay topical medications. Topical medications are widely available in industrialised nations, noninvasive easily transportable. addition, they relatively easy instil need for special equipment or environment. Importantly, unlike non-permanent discontinued if ineffective produces unwanted side effects. pressure lowering was previously known as antiglaucoma drugs. many glaucomatologist deem term inappropriate. do at reverse condition totally halt progression glaucoma. this chapter, drugs will be used. sprouting new more effective has widened choice time cause difficulty selection medication. Table 1.0 provide overview on commonly medication market currently. A guideline discussed chapter.

参考文章(206)
Ingrid A. Adamsons, Adam Polls, Charles S. Ostrov, Janet E. Boyle, Two-year Safety Study of Dorzolamide as Monotherapy and With Timolol and Pilocarpine. Dorzolamide Safety Study Group Journal of Glaucoma. ,vol. 7, pp. 395- 401 ,(1998) , 10.1097/00061198-199812000-00007
Mihaela Mera, Cristina Stan, Oana Vişan, O Samoilă, Lucia Dican, Alexandra Crăciun, The influence of ocular surgery for lacrimal secretion Oftalmologia (Bucharest, Romania). ,vol. 51, pp. 81- ,(2007)
Ritch R, The pilocarpine paradox. Journal of Glaucoma. ,vol. 5, pp. 225- 227 ,(1996)
A. O. Ashaye, O. Fasina, B. G. K. Ajayi, The effect of timolol maleate on tear film break-up time in Nigerians. African journal of medicine and medical sciences. ,vol. 37, pp. 43- 47 ,(2008)
Essy Mozaffari, Tara R. Cockerham, Michael F. Bullano, Thomas Johnson, William J. Waugh, Joshua J. Spooner, Laurence I. Ikeda, Rates of Discontinuation and Change of Glaucoma Therapy in a Managed Care Setting The American Journal of Managed Care. ,vol. 8, ,(2002)
Kramer Sg, Epinephrine distribution after topical administration to phakic and aphakic eyes. Transactions of the American Ophthalmological Society. ,vol. 78, pp. 947- 982 ,(1980)
G O Brindley, J R Sonntag, M B Shields, Effect of timolol therapy on outflow facility. Investigative Ophthalmology & Visual Science. ,vol. 17, pp. 293- 296 ,(1978)
R F Brubaker, R S Larson, Isoproterenol stimulates aqueous flow in humans with Horner's syndrome Investigative Ophthalmology & Visual Science. ,vol. 29, pp. 621- 625 ,(1988)