Diagnosis of systemic sarcoidosis prompted by orofacial manifestations

作者: Mahnaz Fatahzadeh , Joseph Rinaggio

DOI: 10.14219/JADA.ARCHIVE.2006.0021

关键词:

摘要: ABSTRACT Background Sarcoidosis is a multifactorial systemic inflammatory disorder of unknown origin characterized by many potential signs and symptoms, as well the presence noncaseating granulomas in organs involved. also may manifest oral maxillofacial region. Case Description The authors describe patient with xerostomia, dysgeusia, burning, xerophthalmia bilateral parotid enlargement. She was diagnosed having sarcoidosis on basis histologic findings biopsy labial minor salivary gland, subsequent diagnostic evaluations. Conclusion Clinical Implications Enlargement major glands be first sign few other symptoms or clinical suggestive disease. This case emphasizes importance including differential diagnosis swelling associated xerostomia. It highlights dentist's role dental treatment patients sarcoidosis.

参考文章(53)
Chesnutt An, Enigmas in sarcoidosis. Western Journal of Medicine. ,vol. 162, pp. 519- 526 ,(1995)
Millikan Le, Russo G, Cutaneous sarcoidosis: diagnosis and treatment. Comprehensive Therapy. ,vol. 20, pp. 418- 421 ,(1994)
Hilde H. Tillman, Sarcoidosis with unsuspected oral manifestations: Report of a case Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 18, pp. 130- 135 ,(1964) , 10.1016/0030-4220(64)90268-3
Thomas M. Tarpley, Larry Anderson, Philip Lightbody, John N. Sheagren, Minor salivary gland involvement in sarcoidosis. Report of 3 cases with positive lip biopsies. Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 33, pp. 755- 762 ,(1972) , 10.1016/0030-4220(72)90443-4
Alfred P. Fishman, Pulmonary Diseases and Disorders ,(1980)
Lester R. Cahn, Leon Eisenbud, Melvin N. Blake, Diane Stern, BIOPSIES OF NORMAL-APPEARING PALATES OF PATIENTS WITH KNOWN SARCOIDOSIS; A PRELIMINARY REPORT. Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 18, pp. 342- 345 ,(1964) , 10.1016/0030-4220(64)90086-6
Hyman Tannenbaum, Albert L. Sheffer, Earle H. Rosenberg, Larry G. Anderson, Diagnosis of sarcoidosis by lip biopsy of minor salivary glands Canadian Medical Association Journal. ,vol. 111, pp. 1323- 1324 ,(1974)
H. Giotaki, S.H. Constantopoulos, C.S. Papadimitriou, H.M. Moutsopoulos, Labial minor salivary gland biopsy: a highly discriminatory diagnostic method between sarcoidosis and Sjögren's syndrome. Respiration. ,vol. 50, pp. 102- 107 ,(1986) , 10.1159/000194916