Effects of hematopoietic growth factors on purified bone marrow progenitor cells
作者： Freek Bot
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摘要: textabstractWe have used highly enriched hematopoietic progenitor cells and in-vitro culture to examine the following questions: 1. The effects of recombinant lL-3 GM-CSF on proliferation differentiation enriched hematopoietic not been clearly defined: - how do IL~3 GM~CSF compare with respect number types colonies induced? -to what extent accessory influence colony formation induced by IL-3 GM~CSF? {chapters 2 3) 2. G-CSF, M~CSF IL-6 progenitor cells in connection fully elucidated: ~ is the role synergistic between G~CSF, M-CSF IL~6 one hand and other hand, colony forming cells? (chapters 4, 5 6) 3. Consistent results ll-1 immature bone marrow are lacking: ~does directly induce proliferation? -what TNF as mediators IL-1 effect? (chapter 7) 22
参考文章(214)
AG Leary, M Ogawa, Identification of pure and mixed basophil colonies in culture of human peripheral blood and marrow cells Blood. ,vol. 64, pp. 78- 83 ,(1984) , 10.1182/BLOOD.V64.1.78.78
HJ van der Reijden, DJ van Rhenen, PM Lansdorp, MB van't Veer, MM Langenhuijsen, CP Engelfriet, AE von dem Borne, A comparison of surface marker analysis and FAB classification in acute myeloid leukemia Blood. ,vol. 61, pp. 443- 448 ,(1983) , 10.1182/BLOOD.V61.3.443.443
LB To, DN Haylock, CA Juttner, RJ Kimber, None, The effect of monocytes in the peripheral blood CFU-C assay system. Blood. ,vol. 62, pp. 112- 117 ,(1983) , 10.1182/BLOOD.V62.1.112.112
LM Budel, O Elbaz, H Hoogerbrugge, R Delwel, LA Mahmoud, B Lowenberg, IP Touw, Common binding structure for granulocyte macrophage colony-stimulating factor and interleukin-3 on human acute myeloid leukemia cells and monocytes. Blood. ,vol. 75, pp. 1439- 1445 ,(1990) , 10.1182/BLOOD.V75.7.1439.1439
E Vellenga, A Rambaldi, TJ Ernst, D Ostapovicz, JD Griffin, Independent regulation of M-CSF and G-CSF gene expression in human monocytes. Blood. ,vol. 71, pp. 1529- 1532 ,(1988) , 10.1182/BLOOD.V71.6.1529.1529
N Shirafuji, S Matsuda, H Ogura, K Tani, H Kodo, K Ozawa, S Nagata, S Asano, F Takaku, Granulocyte colony-stimulating factor stimulates human mature neutrophilic granulocytes to produce interferon-alpha Blood. ,vol. 75, pp. 17- 19 ,(1990) , 10.1182/BLOOD.V75.1.17.17
JD Griffin, RP Beveridge, SF Schlossman, Isolation of myeloid progenitor cells from peripheral blood of chronic myelogenous leukemia patients. Blood. ,vol. 60, pp. 30- 37 ,(1982) , 10.1182/BLOOD.V60.1.30.30
AA Fauser, HA Messner, Granuloerythropoietic colonies in human bone marrow, peripheral blood, and cord blood Blood. ,vol. 52, pp. 1243- 1248 ,(1978) , 10.1182/BLOOD.V52.6.1243.1243
CF Nathan, Respiratory burst in adherent human neutrophils: triggering by colony- stimulating factors CSF-GM and CSF-G Blood. ,vol. 73, pp. 301- 306 ,(1989) , 10.1182/BLOOD.V73.1.301.BLOODJOURNAL731301
FJ Bot, L Dorssers, G Wagemaker, B Lowenberg, Stimulating spectrum of human recombinant multi-CSF (IL-3) on human marrow precursors: importance of accessory cells. Blood. ,vol. 71, pp. 1609- 1614 ,(1988) , 10.1182/BLOOD.V71.6.1609.1609