High-Grade Gliomas

摘要: The grading of gliomas is important and critical for assessing prognosis planning therapy. A simple system relies upon recognition four parameters: nuclear atypia, mitoses, endothelial proliferation necrosis. presence two or more the above-described features in a glioma places tumor high-grade category [1]. High-grade are tumors with both expansive infiltrative growth [2]. They show some degree anaplasia, without any cleavage plane, microscopic examination cells extend beyond margins. Anaplastic astrocytoma (WHO grade III) glioblastoma multiforme IV), most common primary malignant brain tumors, classified as highgrade tumors. Gliosarcoma, rare IV) composed neoplastic glial sarcomatous component, will be also reviewed Finally, gliomatosis cerebri considered an because poor patients this tumor, while histologically consists lowgrade cells.