Durability and Validity of a Remote, Miniaturized Pressure Sensor in an Animal Model of Abdominal Aortic Aneurysm

摘要: PURPOSE: To investigate whether a remote, miniaturized pressure sensor could maintain calibration and function through organized thrombus over an extended period in porcine model of abdominal aortic aneurysm (AAA). METHODS: Six adult pigs had AAA surgically created excluded. A zeroed to atmospheric was placed within the sac another suprarenal aorta each animal. Pressure measurements were taken at initial operation then on weekly basis 2 months. The sensors correlated intra-arterial catheter time sacrifice. Back-table correlation with done explantation. RESULTS: Three animals died during follow-up period. Five available for 6-week follow-up, which 3 survived complete 8-week protocol. Two surviving intra-aortic sensor. All 5 functioned throughout experimental At sacrifice, sacs contained large amount deeply embedded. also course experiments. pressures mmHg catheter-based Comparison revealed no offset any CONCLUSIONS: This chronic implantation study demonstrates durability as well model. There sensors, they remained valid We believe that this is further evidence potential applicability clinical use.