Xanthan gum derivatives: review of synthesis, properties and diverse applications

摘要: Natural polysaccharides are well known for their biocompatibility, non-toxicity and biodegradability. These properties also inherent to xanthan gum (XG), a microbial polysaccharide. This biomaterial has been extensively investigated as matrices tablets, nanoparticles, microparticles, hydrogels, buccal/transdermal patches, tissue engineering scaffolds with different degrees of success. However, the native XG its own limitations regards susceptibility contamination, unusable viscosity, poor thermal mechanical stability, inadequate water solubility. Chemical modification can circumvent these tailor virgin fulfill unmet needs drug delivery, engineering, oil drilling other applications. review illustrates process chemical and/crosslinking via etherification, esterification, acetalation, amidation, oxidation. further describes tailor-made novel derivatives potential application in diverse fields. The physicomechanical impact on discussed. Overall, recent developments very promising progress polysaccharide research.