Dietary diacylglycerol suppresses accumulation of body fat compared to triacylglycerol in men in a double-blind controlled trial.

摘要: We examined the effects of long-term ingestion dietary diacylglycerols (DG) in a double-blind controlled study human lipid metabolism. Healthy men (n = 38; aged from 27 to 49 y, body mass index (BMI) ranging 21.8 27.4 kg/m(2)) completed study. To accustom subjects test diets prior experiment, they were supplied with triacylglycerol (TG) oil for 4 wk (control period). The oils (10 g/d) included bread, mayonnaise or shortbread and served breakfast. target total intake was 50 g/d (15 g breakfast, 15 lunch 20 dinner) throughout then divided into two groups so that mean BMI hepatic fat content, determined by computed tomography, each group not different. One (DG group) consumed meals containing DG-rich while other (TG same meal as during control period. Ten grams contained 5.5 1,3-DG, 2.5 1,2-DG 2 TG. actual 43 g/d. Body weight, waist circumference decreased both at end period 16 wk. However, magnitudes decreases these variables significantly greater DG than TG group. Decreases fat, visceral area subcutaneous abdominal traverse images tomography also those Hepatic content no change observed Serum concentrations (TG, cholesterol, free fatty acid) related metabolites (glucose, insulin, ketone body) did either Thus, contrast TG, apparently suppressed accumulation possibly reduces risk diseases associated obesity.