Facteurs prédictifs de la récidive postopératoire après résection iléocæcale pour maladie de Crohn

作者: S. Trabelsi , R. Debbeche , S. Bouzaidi , M. Salem , A. Zaouche

DOI: 10.1007/S12157-011-0279-X

关键词:

摘要: Malgre l’efficacite prouvee de plusieurs agents biologiques dans l’induction et le maintien la remission au cours maladie Crohn (MC), pres 80 %des patients necessitent recours a une resection intestinale durant leur vie. Cette chirurgie n’est pas definitivement curative, puisque recidive postoperatoire (RPO) est frequente pose des problemes prise en charge. Evaluer les facteurs predictifs RPO apres ileocaecale (RIC) pour MC. Etude retrospective incluant tous atteints MC ayant subi RIC entre 2000 2009. La lamaladie etait definie par presence signes endoscopiques d’activite l’absence ou symptomes. Afin determiner risque MC, nous avons procede analyse univariee differentes variables rapportees litterature comme influencant l’evolution postoperatoire, suivie d’une multivariee regression logistique. Cinquante-deux ont ete colliges. Une notee chez 15 (28,8 %), un suivi moyen 31,9 mois [1–126]. En univariee, quatre etaient associes eleve RPO: antecedents (ATCD) familiaux maladies inflammatoires chroniques l’intestin (p = 0,007), premiere annee diagnostic 0,004), longueur du grele reseque 0,025) granulome sur piece operatoire 0,035). multivariee, seule retenue facteur independant Apres relativement interesse particulierement operes suivant diagnostic.

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