Seroepidemiology of Human Bocavirus in Hokkaido Prefecture, Japan

摘要: A new human virus, provisionally named bocavirus (HBoV), was discovered by Swedish researchers in 2005. immunofluorescence assay using Trichoplusia ni insect cells infected with a recombinant baculovirus expressing the VP1 protein of HBoV developed, and levels immunoglobulin G antibody to serum samples were measured. The overall seroprevalence rate antibodies against Japanese population aged from 0 months 41 years 71.1% (145 204). seropositive lowest age group 6 8 gradually increased age. All children had been exposed years. rise titers during convalescent phase observed for four patients lower respiratory tract infections, DNA detected nasopharyngeal swab all patients. These results suggest that is ubiquitous virus acquired early life might play role course infections.